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Updated: Jan 8, 2026
A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection
Published on: August 14, 2019
La desnutrición crónica (retraso en el crecimiento) prolonga la excreción del virus de la influenza en niños, lo que
Mia Q Zhu1, Guillermina Kuan2,3, Hannah E Maier1
1Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Abstract:
The role of under-nutrition on influenza virus shedding is unclear. We assessed stunting, an indicator of chronic under-nutrition, as a predictor of shedding duration in children in the Household Influenza Cohort Study, in Managua, Nicaragua. Stunted children, aged 3-9 years, shed influenza longer than their non-stunted peers. In sub-group analysis, associations were driven by H3N2 and influenza B (IB) infections. Analysis of cycle threshold (Ct) values showed slower clearance of IB viruses in stunted children. These findings suggest under-nutrition may prolong influenza shedding, with implications for transmission dynamics and control strategies in low- and middle-income countries where stunting remains prevalent.
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