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Coste de hospitalización de la bacteriemia por Staphylococcus aureus en pediatría
Keerthi Anpalagan1,2, Christopher C Blyth1,2,3,4, Jonathan R Carapetis1,2,3
1School of Medicine, University of Western Australia, Perth, Western Australia, Australia.
Journal of the Pediatric Infectious Diseases Society
|December 19, 2025
Resumen
Las hospitalizaciones por bacteriemia por Staphylococcus aureus (SAB) en la infancia incurren en costos sustanciales, con un promedio de más de 53.000 dólares australianos por caso. Esta carga económica resalta la necesidad de estrategias continuas de prevención y tratamiento dirigidas a S. aureus en niños.
Área de la Ciencia:
- Enfermedades Infecciosas Pediátricas
- Economía de la Salud
- Microbiología Clínica
Sus antecedentes:
- La bacteriemia por Staphylococcus aureus (SAB) es una causa principal de sepsis pediátrica e ingresos en unidades de cuidados intensivos.
- Existen datos limitados sobre el impacto económico de las hospitalizaciones por SAB en la infancia a nivel mundial.
- Este estudio aborda la brecha de conocimiento investigando el costo de las hospitalizaciones por SAB en niños australianos.
Objetivo del estudio:
- Determinar el costo medio de hospitalización para pacientes pediátricos con bacteriemia por Staphylococcus aureus (SAB) en Australia.
- Analizar las variaciones de costos según el inicio comunitario frente al inicio hospitalario de la SAB.
- Proporcionar la primera evaluación económica detallada de las hospitalizaciones por SAB en la infancia.
Principales métodos:
- Análisis económico de los costos de hospitalización de niños (<18 años) con SAB en el Perth Children's Hospital (2017-2018).
- Datos obtenidos de la cohorte de Infecciones e Hospitalizaciones Invasivas por S. aureus (ISAIAH).
- El costo medio de hospitalización se calculó mediante bootstrapping para intervalos de confianza del 95%.
Principales resultados:
- El costo medio de hospitalización para la SAB de inicio comunitario fue de 53.037 dólares australianos por paciente.
- El costo anual total de la SAB de inicio comunitario en PCH se estimó en 1.485.058 dólares australianos.
- La SAB de inicio hospitalario fue significativamente más costosa que la de inicio comunitario.
- La susceptibilidad a los antibióticos no afectó los costos de la SAB de inicio comunitario.
Conclusiones:
- Este estudio presenta el primer análisis económico en profundidad de las hospitalizaciones por SAB en la infancia.
- La carga económica de la SAB en la infancia es sustancial, independientemente de la susceptibilidad a los antibióticos.
- Las estrategias de prevención y tratamiento dirigidas a Staphylococcus aureus siguen siendo cruciales.
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