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¿No hay BCMA? No hay problema: una célula NK CAR dirigida a CD70 muestra promesa en el mieloma múltiple de alto
Don M Benson1, Michael A Caligiuri2
1Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.
Blood cancer discovery
|December 19, 2025
Abstract:
Despite recent advances, multiple myeloma remains essentially incurable for most patients, particularly those with high-risk cytogenetics and those whose disease relapses after BCMA-targeting therapies. A novel CD27 CAR_sIL15 NK cell targeting CD70 may offer new hope in this area of urgent, unmet medical need. See related article by Lin et al., p. XX .
