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Updated: Jan 8, 2026

Live-Cell Forward Genetic Approach to Identify and Isolate Developmental Mutants in Chlamydia trachomatis
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Live-Cell Forward Genetic Approach to Identify and Isolate Developmental Mutants in Chlamydia trachomatis

Published on: June 10, 2020

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Chlamydia trachomatis restringe la señalización a través de NOD2 hasta el final del ciclo de desarrollo del patógeno

Grace Overman1,2, Iris Loeckener3, Zachary Williford1,2

  • 1Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, USA.

Infection and immunity
|December 19, 2025
PubMed
Resumen

Chlamydia trachomatis activa la señalización del dominio 2 que contiene nucleótidos (NOD2) en etapas tardías de la infección, a diferencia de NOD1. Esta señalización tardía puede deberse a la degradación del peptidoglicano durante las transiciones de desarrollo.

Palabras clave:
ChlamydiaNOD2inmunidad innatapatoadaptaciónpeptidoglicanopersistencia

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