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Enfoques de precisión para la hipertensión pediátrica: vinculando la fisiopatología con la terapia
Emily Haseler1,2, Manish D Sinha3,4
1Department of Paediatric Nephrology, Evelina London Children's Hospital, Guys & St Thomas NHS Foundation Trust, Westminster Bridge Road, London, SE1 7EH, UK.
Pediatric nephrology (Berlin, Germany)
|December 19, 2025
Resumen
Comprender la regulación de la presión arterial es clave para tratar la hipertensión. Esta revisión cubre los procesos fisiológicos y su papel en la hipertensión primaria en niños y jóvenes.
Sus antecedentes:
- La presión arterial es el resultado de la función cardíaca y la resistencia arterial.
- Sistemas fisiológicos como el sistema nervioso autónomo y el sistema renina-angiotensina-aldosterona regulan la presión arterial.
- La desregulación de estos sistemas puede causar hipertensión.
Conclusiones:
- Una comprensión integral de la regulación de la presión arterial es crucial para el manejo efectivo de la hipertensión.
- Esta revisión proporciona una base para comprender la hipertensión primaria en niños y adolescentes.
- El conocimiento de los fundamentos fisiológicos ayuda a seleccionar terapias antihipertensivas apropiadas.
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