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Serotipos de dengue y dinámicas epidémicas en Brasil: una perspectiva espaciotemporal

Camila Lorenz¹, Philippe Lemey², Simon Dellicour³

¹Department of Parasitology, Instituto Butantan, São Paulo, Sao Paulo, Brazil; Department of Epidemiology, School of Public Health of University of Sao Paulo, Brazil.

Travel medicine and infectious disease

|December 19, 2025

Resumen

Los casos de dengue están aumentando en Brasil debido a la propagación del mosquito Aedes aegypti y a múltiples serotipos del virus del dengue (DENV). Este estudio analiza la distribución de los serotipos de DENV y discute las estrategias de mitigación.

Área de la Ciencia:

Epidemiología
Entomología Médica
Virología

Sus antecedentes:

La expansión geográfica de Aedes aegypti, el principal vector del dengue, está aumentando la transmisión de la enfermedad en Brasil.
La circulación concurrente de múltiples serotipos del virus del dengue (DENV) complica los esfuerzos de control de la enfermedad.
Brasil ha experimentado un aumento significativo en la incidencia de dengue en la última década.

Objetivo del estudio:

Investigar la distribución espaciotemporal de los serotipos de DENV en todo Brasil desde 2014 hasta 2025.
Analizar la dinámica temporal de la circulación de los serotipos de DENV.
Discutir estrategias de salud pública para mitigar el impacto de los serotipos de DENV cocirculantes.

Principales métodos:

Análisis espaciotemporal de datos de serotipos de DENV.
Análisis de tendencias epidemiológicas durante un período definido.
Revisión de estrategias de intervención de salud pública.

Principales resultados:

Mapeo detallado de la distribución de los serotipos de DENV y sus cambios a lo largo del tiempo.
Identificación de patrones en la cocirculación de diferentes serotipos de DENV.
Evaluación del impacto epidemiológico de la expansión del vector y la diversidad de serotipos.

Conclusiones:

Comprender la dinámica de los serotipos de DENV es crucial para la prevención eficaz del dengue en Brasil.
Se necesitan estrategias integradas para abordar el control de vectores y el reemplazo de serotipos.
La preparación de la salud pública debe adaptarse a la epidemiología cambiante del dengue en Brasil.

Palabras clave:

dengue Aedes aegypti Brasil serotipos de DENV dinámica epidémica espaciotemporal incidencia

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