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Moldeando la memoria desde el principio: Errores de predicción iniciales durante la primera codificación

Nina Liedtke1, Marius Boeltzig1, Sophie Siestrup1

  • 1Department of Psychology, University of Münster, Fliednerstraße 21, 48149 Münster, Germany; Otto Creutzfeldt Center for Cognitive and Behavioral Neuroscience, University of Münster, Germany.

NeuroImage
|December 19, 2025
PubMed
Resumen
Este resumen es generado por máquina.

Los errores de predicción iniciales (EP), derivados de experiencias individuales, influyen en la codificación de la memoria de manera similar a los EP experimentales. Estos hallazgos resaltan la importancia de considerar los EP individuales en la investigación de la memoria.

Palabras clave:
memoria episódicafMRIestabilidad de la memoriaerror de predicción

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Área de la Ciencia:

  • Neurociencia
  • Psicología Cognitiva
  • Investigación de la Memoria

Sus antecedentes:

  • El cerebro predice continuamente la información sensorial entrante.
  • Los errores de predicción (EP) señalan la entrada inesperada y mejoran la codificación de la memoria.
  • El papel de los EP evocados por la exposición inicial a estímulos novedosos, basados en factores individuales, en la memoria sigue sin estar claro.

Objetivo del estudio:

  • Investigar los efectos neuronales y mnémicos de los EP iniciales.
  • Examinar cómo interactúan los EP iniciales con los EP inducidos experimentalmente.
  • Comprender la influencia del conocimiento y las creencias individuales en el procesamiento de errores de predicción.

Principales métodos:

  • Escaneo fMRI durante la presentación de estímulos auditivos (diálogos naturalistas).
  • Inducción de un EP inicial seguido de un EP experimental a través de la modificación del diálogo.
  • Prueba de memoria de reconocimiento para estímulos originales y modificados.

Principales resultados:

  • Los EP iniciales, similares a los EP experimentales, redujeron la reinstauración predictiva de arriba hacia abajo y aumentaron la activación de la corteza auditiva de abajo hacia arriba.
  • Los aspectos semánticos de los EP iniciales y experimentales mejoraron el aprendizaje.
  • La activación del giro frontal inferior (GFI) sesgó el recuerdo de la memoria hacia las representaciones activas actualmente.

Conclusiones:

  • Proporciona la primera evidencia de la existencia y la importancia de los EP iniciales en la codificación de la memoria.
  • Sugiere que los EP iniciales, influenciados por experiencias personales, impactan los procesos de memoria.
  • Recomienda incorporar los EP individuales en los paradigmas que estudian la memoria episódica y los errores de predicción.