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Navegación de necesidades básicas intervención para abordar la adversidad multidimensional en afroamericanos con
Mukoso N Ozieh1, Charity G Patterson2, Joni S Williams3
1Department of Medicine, Division of Nephrology, Medical College of Wisconsin, 8701 Watertown Plank Rd., Milwaukee, WI 53226, USA; Department of Medicine, Division of Nephrology, Clement J. Zablocki VA Medical Center, Milwaukee, WI 53295, USA; Center for Advancing Population Science, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA.
Contemporary clinical trials
|December 19, 2025
Resumen
Este estudio piloto evalúa una intervención de navegación de necesidades básicas para afroamericanos con enfermedad renal diabética (ERD) que enfrentan adversidad social. Su objetivo es determinar la viabilidad de la intervención e informar futuros ensayos a gran escala para un mejor manejo de la ERD.
Área de la Ciencia:
- Nefrología; Salud Pública; Disparidades en Salud
Sus antecedentes:
- La enfermedad renal diabética (ERD) afecta de manera desproporcionada a los afroamericanos, lo que lleva a la enfermedad renal terminal (ERT).
- Las adversidades sociales complican el autocontrol de la ERD y empeoran los resultados de salud.
- Las intervenciones de navegación del paciente muestran ser prometedoras para el manejo de enfermedades crónicas.
Objetivo del estudio:
- Evaluar la viabilidad de una intervención de navegación de necesidades básicas para adultos afroamericanos con ERD y adversidad social.
- Evaluar el impacto de la intervención en los resultados clínicos y centrados en el paciente.
- Recopilar datos para un ensayo clínico aleatorizado más grande y potenciado.
Principales métodos:
- Un ensayo clínico aleatorizado piloto de 3 años y dos brazos.
- Reclutamiento de 50 adultos afroamericanos con ERD y diabetes no controlada (HbA1c ≥ 8%).
- Brazo de intervención: navegación de necesidades básicas, educación del paciente y entrenamiento en estilo de vida; Brazo de control: atención habitual mejorada.
Principales resultados:
- El resultado primario es la viabilidad de la intervención de navegación de necesidades básicas, medida por las tasas de reclutamiento, asistencia y retención.
- Los datos informarán el diseño de un ensayo clínico aleatorizado a gran escala y adecuadamente potenciado.
- Este estudio aborda una brecha crítica en la comprensión de cómo manejar la ERD en poblaciones vulnerables.
Conclusiones:
- Este ensayo piloto proporciona datos esenciales de viabilidad para una intervención novedosa.
- Los hallazgos guiarán la investigación futura sobre cómo abordar la adversidad social en adultos afroamericanos con ERD.
- El estudio es un primer paso crucial hacia la mejora de los resultados de salud para esta población de alto riesgo.
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