Video Experimental Relacionado

Updated: Jul 24, 2026

Effects of Transcranial Alternating Current Stimulation on the Primary Motor Cortex by Online Combined Approach with Transcranial Magnetic Stimulation

Effects of Transcranial Alternating Current Stimulation on the Primary Motor Cortex by Online Combined Approach with Transcranial Magnetic Stimulation

Published on: September 23, 2017

Efectos de la Estimulación Transcraneal por Pulsos de la Corteza Motora Primaria en el Rendimiento Motor en Adultos

Penny Ping Qin¹, Ivan Kin-Yeung Chak¹, Rebecca Lai-Di Kan¹

¹Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China.

CNS neuroscience & therapeutics

|December 20, 2025

Abstracto

Aims:

We aimed to investigate the behavioral aftereffects of a novel noninvasive brain stimulation technique-transcranial pulse stimulation (TPS)-applied over the right motor cortex (rM1) in healthy adults.

Methods:

Thirty-four healthy adults underwent a randomized, subject- and analyst- blind, crossover trial, receiving active TPS over the rM1 or control TPS over the vertex in two sessions 24 h apart. Motor performance was assessed using the Nine-Hole Peg Test (NHPT) and the Simple Reaction Time Task (SRTT) before, immediately after, and every 10 min for 40 min after each session. A linear mixed model and post hoc analyses were applied to evaluate the effects.

Results:

No significant interaction effect (stimulation condition × time) was found. The left-hand NHPT performance significantly improved from 10 min post-TPS onward in both conditions (ps ≤ 0.002).

Conclusion:

A single session of rM1-TPS does not yield significant improvements in motor dexterity compared to vertex-TPS. Future well-powered studies with a sham control condition and multiple stimulation sessions are needed to investigate the aftereffects using a combination of neurophysiological and neuroimaging approaches.

Trial Registration:

This study was registered in ClinicalTrial.gov in April 2024 (NCT06312930).

Palabras clave:

corteza motora función motora estimulación cerebral no invasiva estimulación transcraneal por pulsos

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