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Microbiota Modulation by Antibiotics01:21

Microbiota Modulation by Antibiotics

Antibiotics have revolutionized modern medicine by saving countless lives from bacterial infections. However, their widespread use has inadvertently harmed the delicate balance of the human gut microbiota. The gut microbiota, a complex community of bacteria, archaea, viruses, and fungi, plays a vital role in regulating metabolism, immune responses, and maintaining intestinal health. Antibiotics, especially broad-spectrum types, disrupt this ecosystem by eradicating both harmful and beneficial...

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Intraductal Injection of LPS as a Mouse Model of Mastitis: Signaling Visualized via an NF-κB Reporter Transgenic
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Transcriptómica unicelular revela un microambiente inmunitario anómalo en la mastitis de células plasmáticas

Qingtao Ni1, Gaohua Han1, Chi Pan2

  • 1Department of Oncology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China.

Annals of medicine
|December 20, 2025
PubMed
Resumen

Este estudio proporciona un análisis celular y molecular detallado de la mastitis de células plasmáticas (MCP), revelando alteraciones clave de las células inmunitarias y cambios en la expresión génica. Los hallazgos ofrecen un recurso fundamental para comprender la patogénesis de la MCP y desarrollar nuevos tratamientos.

Palabras clave:
Transcriptómica unicelularmicroambiente inmunitariomastitis de células plasmáticasvía de señalización

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