Video Experimental Relacionado

Updated: Jan 8, 2026

NMR-Based Fragment Screening in a Minimum Sample but Maximum Automation Mode
09:19

NMR-Based Fragment Screening in a Minimum Sample but Maximum Automation Mode

Published on: June 4, 2021

3.7K

Descubrimiento de ligandos de ARN: Aprovechamiento de la RMN para la generación de éxitos

Alexandra Gaspar1, Jorge M P J Garrido2

  • 1CIQUP-IMS, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007, Porto, Portugal.

European journal of medicinal chemistry
|December 21, 2025
PubMed
Resumen

El ARN es un objetivo terapéutico emergente más allá de las proteínas. La espectroscopía de resonancia magnética nuclear (RMN) ayuda a descubrir fármacos dirigidos al ARN y a comprender sus interacciones para el desarrollo clínico.

Palabras clave:
Interacciones biomolecularesTécnicas biofísicasCribado basado en RMN de ligandosDescubrimiento de fármacos dirigidos al ARNMoléculas pequeñas

Más Videos Relacionados

Author Spotlight: Unveiling the Structural and Dynamic Aspects of Glycan Molecular Recognition07:40

Author Spotlight: Unveiling the Structural and Dynamic Aspects of Glycan Molecular Recognition

Published on: May 17, 2024

1.9K
Exploring Protein-Glycan Interactions: Advances in Nuclear Magnetic Resonance10:07

Exploring Protein-Glycan Interactions: Advances in Nuclear Magnetic Resonance

Published on: August 26, 2025

498

Videos de Conceptos Relacionados

Ligand Binding Sites02:40

Ligand Binding Sites

Proteins are dynamic macromolecules that carry out a wide variety of essential processes; however, the activities of most proteins depend on their interactions with other molecules or ions, known as ligands.
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...
14.8K
Applications Of NMR In Biology01:25

Applications Of NMR In Biology

Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
4.4K