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Updated: Jul 3, 2026

Study of Viral Vectors in a Three-dimensional Liver Model Repopulated with the Human Hepatocellular Carcinoma Cell Line HepG2
Published on: October 24, 2016
Diseño de una novedosa estructura neuronal de base radial para resolver el modelo dinámico del virus de la hepatitis
Zulqurnain Sabir1, Adilkazy Yessengaliyev2, Abdikhalyk Temirzhan2
1Department of Computer Science and Mathematics, Lebanese American University, Beirut, Lebanon.
Abstract:
The purpose of the current investigation is to design a novel radial basis neural network for solving the dynamical hepatitis C virus model in patients with a high baseline viral load, which represents the nonlinear dynamical structure. The infection and treatment in the hepatitis C virus comprise uninfected hepatocytes, creatively infected hepatocytes, and viruses. The aim of this study is to solve the dynamical hepatitis C virus model in patients with a high baseline viral load with the optimization of the Bayesian regularization scheme. A database reference solution is achieved by the explicit Runge-Kutta in interval 0 and 1 with the step size of 0.01 by data division into training as 72%, while 14%, 14% for endorsement, and testing. Twenty numbers of neurons, a feed forward neural network, activation radial basis function, and the optimization Bayesian regularization approach have been used to solve the hepatitis C virus model. The precision of the scheme is perceived by the outcomes overlapping and the reducible absolute error values, which are found as 10-06 to 10-08. A statistical evaluation utilizing various operators and proportional approaches is carried out in order to assess the solver's efficiency.
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