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Updated: Jan 8, 2026

Noninvasive, High-throughput Determination of Sleep Duration in Rodents
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Actividad circadiana y arquitectura del sueño en un modelo de ratón de trastorno del espectro autista con mutación

Jiahui Yu1,2,3, Norie Deki-Arima1,3, Yuki C Saito1,3

  • 1International Institute for Integrative Sleep Medicine (WPI-IIIS), Tsukuba Institute for Advanced Research (TIAR), University of Tsukuba, Tsukuba, Ibaraki, Japan.

Frontiers in sleep
|December 22, 2025
PubMed
Resumen

Los ratones con mutaciones en el gen CHD8, relacionado con el trastorno del espectro autista (TEA), presentan alteraciones significativas del sueño. Estas incluyen patrones alterados de sueño de movimientos oculares rápidos (MOR) y una reducción de la actividad nocturna, lo que ofrece información sobre los problemas de sueño relacionados con el TEA.

Palabras clave:
CHD8ratones Chd8 knockoutEEGtrastorno del espectro autista (TEA)sueño

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