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Updated: Jan 8, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Protocolo de Manejo Perioperatorio de la Miocardiopatía Isquémica en un Hospital Comunitario
Katherine Slusarz1,2, Brock Daughtry3, Jeremy London2
1Department of Cardiothoracic Surgery, Brigham and Women's Hospital, Boston, Massachusetts.
Background:
We describe our experience using a defined protocol for the selection, classification, and treatment of patients with ischemic cardiomyopathy (ICM) undergoing coronary artery bypass grafting (CABG), with or without additional procedures, in a nonacademic setting with expected limited resources and support staff.
Methods:
From December 2021 to December 2023, 25 patients with an ejection fraction of ≤0.44 due to ICM requiring CABG were assigned to a treatment algorithm based on the preoperative classification for CABG with no device (n = 9), balloon pump (n = 2), or direct centrifugal pump (n = 14) placed in the operating room.
Results:
Preliminary data of all patients with surgically revascularized ICM using the defined protocol demonstrated a predicted average risk of mortality of 8.455% vs our mortality rate of 4%, whereas the average predicted risk of morbidity and mortality was 27.7%, with our 30-day morbidity and mortality of 24%. Subgroup analysis of the 3 patient categories: moderately depressed, low risk; moderately depressed, high risk; and severely depressed; shows better-than-expected outcomes when compared with predictions.
Conclusions:
In a community hospital setting, experience using a defined protocol to select and manage patients with ICM undergoing CABG reduced morbidity and mortality compared with predicted outcomes. This is a practical method of managing high-risk CABG patients with the expected limitations of a community hospital.
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