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Updated: Jan 8, 2026

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles

Published on: November 10, 2017

Implementación de las Guías de Dislipidemia en la Práctica Clínica Tras un Síndrome Coronario Agudo: Desafíos y

Alisha Labinaz¹, Ren Jie Robert Yao¹, Farshad Hosseini¹

¹Division of Cardiology, Department of Medicine, and the Centre for Cardiovascular Innovation, University of British Columbia, Vancouver, British Columbia, Canada.

|December 22, 2025

Abstract:

Following an acute coronary syndrome (ACS), patients remain at a residual increased risk of adverse cardiovascular events. As such, secondary prevention strategies, including dyslipidemia management, are key in the delivery of post-ACS care. Multiple randomized controlled trials have highlighted the benefit of lipid-lowering therapies in reducing low-density lipoprotein cholesterol levels, an independent predictor of adverse cardiovascular events post-ACS. However, registries have demonstrated that post-ACS, a significant proportion of patients are not achieving guideline-recommended low-density lipoprotein target levels, and intensification of lipid-lowering therapies continues to be underutilized. This review assesses strategies in which post-ACS lipid management can be improved, in particular by standardizing follow-up care through dedicated post-ACS clinics.

Palabras clave:

Dislipidemia síndrome coronario agudo terapias hipolipemiantes clínicas post-síndrome coronario agudo prevención secundaria

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