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ERC en la encrucijada: de los fracasos a las terapias futuras
Farah Wehbe1, Mark Elliott1, Adeera Levin1
1Division of Nephrology, Department of Medicine, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Kidney international reports
|December 22, 2025
Resumen
Los tratamientos para la enfermedad renal crónica (ERC) están avanzando, pero su adopción es baja. Esta revisión cubre las terapias actuales y emergentes, las barreras de implementación y las estrategias de manejo personalizadas para pacientes con ERC.
Sus antecedentes:
- La enfermedad renal crónica (ERC) presenta un desafío significativo para la salud global debido a su alta prevalencia y mortalidad asociada.
- Las opciones de tratamiento para la ERC eran históricamente limitadas, pero los avances recientes han introducido múltiples terapias aprobadas y nuevos candidatos a fármacos prometedores.
- A pesar de la sólida evidencia que respalda los tratamientos actuales para la ERC, su adopción clínica es subóptima, lo que limita el beneficio para el paciente.
Conclusiones:
- La optimización del manejo de la ERC requiere superar las barreras de implementación y adoptar un enfoque personalizado para la selección de la terapia.
- Los ensayos clínicos en curso son cruciales para expandir las opciones terapéuticas e informar el uso clínico rutinario.
- Abordar los desafíos globales de acceso y asequibilidad es esencial para una atención equitativa de la ERC.
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