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Updated: Jan 8, 2026

Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-phosphinetriyltripiperidine]}palladium Under Mild Reaction Conditions

Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-phosphinetriyltripiperidine]}palladium Under Mild Reaction Conditions

Published on: March 20, 2014

Acoplamiento Cruzado de Bromuros de Alquinilo y Policlorosilanos Mediado por Zn

Pan Pan¹, Jingcao Li², Yan-Lin Zhang³

¹Biomass Oligosaccharides Engineering Technology Research Center of Anhui Province, School of Chemical and Material Engineering, Fuyang Normal University, Fuyang 236037, China.

The Journal of organic chemistry

|December 23, 2025

Resumen

Un nuevo método sintetiza alquinilsilanos utilizando catálisis de zinc, evitando metales de transición y ligandos. Este proceso eficiente produce diversos alquinilsilanos a partir de precursores simples para modificaciones químicas posteriores.

Sus antecedentes:

Los alquinilsilanos son bloques de construcción versátiles en síntesis orgánica.
Los métodos existentes para la síntesis de alquinilsilanos a menudo requieren metales de transición o ligandos específicos, lo que limita su practicidad.
El desarrollo de rutas sintéticas libres de metales y ligandos es muy deseable.

Conclusiones:

El protocolo desarrollado proporciona un enfoque práctico y general para la síntesis de alquinilsilanos.
El método evita la necesidad de metales de transición y ligandos, ofreciendo una alternativa más ecológica.
Los alquinilsilanos resultantes son susceptibles a diversas funcionalizaciones posteriores, lo que amplía su utilidad sintética.

Palabras clave:

alquinilsilanos acoplamiento cruzado química organometálica síntesis orgánica química sostenible

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