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Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
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Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
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Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
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Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
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There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
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At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
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Updated: Jan 8, 2026

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
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Salud Pública

Jacob F Reusch1, Kristen M Farris1, Jasroop K Miglani1

  • 1University of Washington School of Medicine, Seattle, WA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
PubMed
Resumen
Este resumen es generado por máquina.

En adultos mayores sin diabetes, niveles más altos de Hemoglobina A1C (HbA1c) se correlacionaron con una mejor función cognitiva en no portadores de APOE4 pero con una peor función en portadores de APOE4. Esto resalta la compleja interacción entre la salud metabólica y el riesgo genético de deterioro cognitivo.

Palabras clave:
Salud PúblicaGenéticaMetabolismoNeurocienciaEnfermedad de AlzheimerDeterioro CognitivoAPOE4HbA1cAdultos Mayores

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Área de la Ciencia:

  • Neurociencia
  • Salud Metabólica
  • Genética

Sus antecedentes:

  • La diabetes es un factor de riesgo conocido para la enfermedad de Alzheimer.
  • La relación entre el riesgo de diabetes y el genotipo APOE4 no se comprende bien.
  • Ensayos en curso exploran medicamentos para la diabetes para la prevención de la demencia.

Objetivo del estudio:

  • Investigar la asociación entre los factores metabólicos y el rendimiento cognitivo en adultos mayores sin diabetes.
  • Examinar el papel del genotipo APOE4 en esta relación.

Principales métodos:

  • 139 adultos mayores sin diabetes se sometieron a cribado metabólico.
  • Los participantes completaron la Batería de Cognición NIH Toolbox (NIHTB-CB) después de una intervención alta en grasas.
  • Se utilizaron modelos lineales generales y ANOVAs para analizar los factores metabólicos, el estado de APOE4 y la cognición.

Principales resultados:

  • La hemoglobina A1C (HbA1c) predijo individualmente el rendimiento en varias pruebas cognitivas.
  • Se encontró una interacción significativa entre la HbA1c y el estado de APOE4 en el rendimiento cognitivo.
  • Una HbA1c más alta predijo un mejor rendimiento cognitivo en no portadores de E4 pero un peor rendimiento en portadores de E4.

Conclusiones:

  • El estado de APOE4 interactúa con la HbA1c en adultos mayores cognitivamente normales sin diabetes.
  • Esta interacción influye en el rendimiento cognitivo, con efectos opuestos según el estado de portador de APOE4.
  • Comprender estas interacciones metabólico-genómicas es crucial para las estrategias de evaluación y prevención del riesgo de la enfermedad de Alzheimer.