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Salud Pública

Debora Melo van Lent^1,2, Daniel Koijs^3,4,5, Josh Bis⁶

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Resumen

Este resumen es generado por máquina.

Adherirse a la dieta Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) se relaciona con un menor riesgo de demencia. Las puntuaciones más altas en la dieta MIND también aumentan la probabilidad de permanecer libre de demencia a los 80 años.

Palabras clave:

dieta MIND demencia salud pública nutrición enfermedades neurodegenerativas

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Área de la Ciencia:

Neurociencia; Ciencia Nutricional; Epidemiología

Sus antecedentes:

Estudios observacionales sugieren una relación entre la dieta Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) y la reducción del riesgo de demencia.; La dieta MIND combina aspectos de las dietas mediterránea y DASH, centrándose en alimentos beneficiosos para el cerebro.

Objetivo del estudio:

Investigar la asociación entre las puntuaciones de la dieta MIND y el riesgo de demencia incidente por todas las causas.; Examinar la relación entre las puntuaciones de la dieta MIND y la probabilidad de estar vivo y libre de demencia a los 80 años.

Principales métodos:

Análisis de datos de 8.714 adultos sin demencia de seis cohortes comunitarias.; Se utilizaron modelos de regresión de Cox y logística, y los resultados se combinaron mediante metaanálisis.; Las puntuaciones de la dieta MIND se calcularon en base a diez componentes dietéticos saludables y cinco no saludables.

Principales resultados:

Las puntuaciones más altas en la dieta MIND se asociaron con una disminución del riesgo de demencia por todas las causas (HR=0.96, IC 95%=0.93-0.99).; Las puntuaciones de la dieta MIND de 6 o más mostraron una reducción significativa en el riesgo de demencia (HR=0.86, IC 95%=0.78-0.94).; Las puntuaciones más altas en la dieta MIND se correlacionaron con mayores probabilidades de estar vivo y libre de demencia a los 80 años (OR=1.11, IC 95%=1.07-1.15).

Conclusiones:

La dieta MIND se asocia con un menor riesgo de demencia por todas las causas.; Una mayor adherencia a la dieta MIND se relaciona con una mayor probabilidad de permanecer libre de demencia a los 80 años.; Se recomiendan más ensayos clínicos para explorar una posible relación causal entre la dieta MIND y las patologías de la demencia, incluidos los marcadores de amiloide y tau.