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Xinyi Qian^1,2, Bo Hong^1,2, Shifu Xiao^1,2

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Resumen

Este resumen es generado por máquina.

Agitación en el Alzheimer

Palabras clave:

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Área de la Ciencia:

Psiquiatría Geriátrica
Neurociencia
Psicología Clínica

Sus antecedentes:

La agitación es un síntoma común y angustiante en la enfermedad de Alzheimer (AD).
Comprender las influencias multifactoriales sobre la agitación es crucial para un manejo efectivo.
Identificar factores modificables puede conducir a intervenciones específicas.

Objetivo del estudio:

Investigar el impacto de los factores del cuidador, ambientales e individuales en la agitación en pacientes con AD.
Identificar los factores clave modificables asociados con los síntomas de agitación.

Principales métodos:

Se reclutó una cohorte de 110 pacientes con enfermedad de Alzheimer y sus cuidadores principales.
La recopilación de datos incluyó pruebas neuropsicológicas del paciente (MMSE, GDS), evaluaciones del cuidador (NPI, Escalas de Hamilton), cuestionarios ambientales y gravedad de la agitación (Inventario de Agitación de Cohen-Mansfield).
Los análisis estadísticos examinaron las diferencias entre los grupos con y sin agitación e identificaron los factores asociados con la agitación.

Principales resultados:

Más de la mitad (56,36%) de los pacientes con AD exhibieron agitación.
La agitación se asoció con pacientes varones, cuidadores mujeres, falta de vistas al patio/jardín, puntuaciones MMSE más bajas y puntuaciones GDS más bajas.
Los factores protectores contra la agitación incluyeron habitaciones con vistas al patio/jardín, cuidadores varones y puntuaciones MMSE más altas.

Conclusiones:

Mejorar el entorno de vida, alentar a los cuidadores varones y mejorar el apoyo al cuidador puede reducir la agitación en la AD.
Se recomiendan intervenciones multifactoriales que involucren a profesionales de la salud, comunidades y familias.
Dirigirse a factores modificables ofrece un enfoque prometedor para el manejo de la agitación en la enfermedad de Alzheimer.