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Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
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Salud Pública
1Brighton and Sussex Medical School, Brighton, United Kingdom.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
Resumen
Comprender el momento del diagnóstico de la demencia es crucial. Los factores sociodemográficos tienen efectos complejos, directos e indirectos, sobre el diagnóstico temprano y oportuno de la demencia, que varían según la definición.
Área de la Ciencia:
- Gerontología
- Salud Pública
- Investigación sobre demencia
Sus antecedentes:
- Existe evidencia limitada sobre los factores sociodemográficos que influyen en el momento del diagnóstico de la demencia.
- Los métodos de regresión tradicionales pasan por alto las vías indirectas en la investigación del momento del diagnóstico.
- Ningún estudio ha mapeado de manera integral los factores directos e indirectos para el diagnóstico temprano y oportuno de la demencia.
Objetivo del estudio:
- Investigar los determinantes sociodemográficos directos e indirectos del diagnóstico temprano y oportuno de la demencia.
- Explorar las variaciones en el momento del diagnóstico según medidas cognitivas y temporales.
- Diferenciar los factores asociados con los diagnósticos de demencia 'tempranos' frente a 'oportunos'.
Principales métodos:
- Se utilizaron datos de referencia del estudio DETERMINED (940 personas con demencia, 698 cuidadores).
- Se desarrollaron índices para el diagnóstico temprano (gravedad cognitiva, tiempo desde el inicio de los síntomas hasta el diagnóstico) y el diagnóstico oportuno (informes de pacientes/cuidadores).
- Se empleó un análisis de vías complejas para examinar las asociaciones directas e indirectas de las variables de fondo con el momento del diagnóstico.
Principales resultados:
- Los determinantes sociodemográficos mostraron efectos variados y a veces contradictorios en las vías de diagnóstico.
- El diagnóstico temprano de demencia en términos cognitivos fue más común en díadas de blancos; el diagnóstico temprano en términos temporales fue más común en personas no blancas.
- Se identificaron determinantes distintos para los diagnósticos de demencia tempranos frente a los oportunos.
Conclusiones:
- El análisis de vías complejas proporcionó nuevas perspectivas sobre los factores sociodemográficos que afectan el momento del diagnóstico de la demencia.
- La operacionalización del diagnóstico 'temprano' es vital para obtener resultados de investigación consistentes y comprender el momento del diagnóstico.
- El diagnóstico temprano no significa inherentemente un diagnóstico 'oportuno'; estos términos no son intercambiables en la investigación o la política.
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