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Salud Pública
Iñigo Tellaetxe Elorriaga1,2, Eukene Imatz3, Bergoi Ibarlucea3
1Biobizkaia HRI, Barakaldo, Bizkaia, Spain.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 23, 2025
Resumen
El proyecto ITTHACA tiene como objetivo mejorar el envejecimiento saludable a través de un enfoque multimodal, desarrollando biomarcadores, biosensores y modelos predictivos. Esta iniciativa busca identificar marcadores tempranos de envejecimiento y deterioro cognitivo para intervenciones oportunas.
Área de la Ciencia:
- Gerontología y Salud Pública; Descubrimiento de biomarcadores; Investigación interdisciplinaria
Sus antecedentes:
- El proyecto ITTHACA es una iniciativa colaborativa en el País Vasco, que se basa en el estudio CITA Go-On.
- Adapta el modelo finlandés FINGER para promover el envejecimiento saludable mediante la identificación de marcadores y el desarrollo de intervenciones.
Objetivo del estudio:
- Identificar biomarcadores, desarrollar modelos de predicción y crear sensores para el monitoreo in vivo del envejecimiento.
- Establecer e implementar estrategias de intervención combinadas para mejorar el envejecimiento saludable en la población.
Principales métodos:
- Un ensayo controlado aleatorizado de un año que involucra a 250 participantes de 60 a 85 años en riesgo de demencia.
- El análisis de biomarcadores incluye proteómica, metabolómica, metagenómica y lipidómica.
- Desarrollo de tecnología de biosensores y modelado predictivo que integra múltiples dominios de salud.
Principales resultados:
- El proyecto ITTHACA está en curso; los resultados esperados incluyen biomarcadores validados, biosensores novedosos y modelos predictivos.
- Estas herramientas están destinadas a facilitar intervenciones tempranas para afecciones relacionadas con el envejecimiento.
Conclusiones:
- ITTHACA destaca el valor de la colaboración interdisciplinaria para abordar el desafío multifacético del envejecimiento.
- El proyecto tiene como objetivo generar recursos innovadores para prolongar la vida saludable y autónoma y apoyar nuevas estrategias terapéuticas.
Palabras clave:
envejecimiento saludablebiomarcadoresbiosensoresmodelos predictivosintervención tempranasalud públicagerontologíaestudio FINGERensayo controlado aleatorizadovascosMás Videos Relacionados
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