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Codificación cortical y estriatal complementaria de la preparación y el rendimiento locomotor
Deepak Singla1, Long Yang2, Andrew S Weakley1
1Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.
iScience
|December 24, 2025
Resumen
Este estudio revela una codificación neuronal distinta para la preparación y ejecución de la marcha en el cerebro. El estriado dorsomedial destaca en la codificación de la preparación, mientras que la corteza motora y el estriado dorsolateral representan mejor los movimientos de las extremidades durante la locomoción.
Sus antecedentes:
- Los circuitos corticales y estriatales son cruciales para el control motor, exhibiendo dinámicas neuronales similares.
- Las comparaciones directas de cómo estos circuitos codifican la preparación y ejecución de la locomoción son limitadas.
Conclusiones:
- Los circuitos corticales y estriatales emplean esquemas de codificación complementarios para la preparación y el rendimiento de la locomoción.
- Existen especializaciones regionales distintas para codificar diferentes aspectos de la locomoción.
- Esto proporciona información sobre la base neuronal del control y la planificación motora.
Palabras clave:
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