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Updated: Jan 8, 2026
Production of E. coli-expressed Self-Assembling Protein Nanoparticles for Vaccines Requiring Trimeric Epitope Presentation
Published on: August 21, 2019
Mejora de las respuestas de anticuerpos funcionales contra la envoltura V1V2 del VIH mediante formulaciones de
Clauvis Kunkeng Yengo1,2, Xiaomei Liu1,2, Gabriel Laghlali3,4,5
1James J. Peters VA Medical Center, Bronx, NY, United States.
Se están desarrollando formulaciones novedosas de vacunas dirigidas al dominio V1V2 del VIH para inducir anticuerpos funcionales. Los adyuvantes de nanopartículas lipídicas (LNP), en particular el ARNm-LNP, prometen generar respuestas de anticuerpos robustas y cruzadas para mejorar la eficacia de las vacunas contra el VIH.
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