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Prevalencia y tipos de rasgos tratables en la bronquiectasia: un estudio multicéntrico y transversal
Marianna Cicchetti1,2, Alessandro De Angelis3,4,2, Edoardo Simonetta4
1Respiratory Diseases Section, Department of Basic Medical Science, Neuroscience and Sense Organs, Aldo Moro University of Bari, AOUC Policlinico of Bari, Bari, Italy.
ERJ open research
|December 24, 2025
Resumen
La identificación de diversos rasgos tratables en la bronquiectasia es clave. El reconocimiento de estas características específicas del paciente permite una atención personalizada, mejores resultados y un uso eficiente de los recursos en la práctica clínica.
Área de la Ciencia:
- Neumología
- Medicina Clínica
- Neumología
Sus antecedentes:
- La bronquiectasia es una afección pulmonar crónica caracterizada por inflamación e infección persistentes de las vías respiratorias.
- La presentación del paciente y la progresión de la enfermedad en la bronquiectasia muestran una heterogeneidad significativa.
- Las estrategias de manejo actuales tienen como objetivo abordar los síntomas y prevenir las exacerbaciones, pero los enfoques personalizados están en evolución.
Objetivo del estudio:
- Identificar y categorizar la diversa gama de rasgos tratables observados en pacientes con bronquiectasia.
- Destacar la importancia de reconocer la heterogeneidad del paciente en la adaptación de los planes de tratamiento.
- Proporcionar un marco para optimizar la práctica clínica y la asignación de recursos en función de las necesidades individuales del paciente.
Principales métodos:
- Revisión sistemática de la literatura sobre fenotipos de bronquiectasia y rasgos tratables.
- Análisis de datos clínicos para identificar características tratables comunes y poco comunes.
- Desarrollo de un sistema de clasificación para rasgos tratables en la bronquiectasia.
Principales resultados:
- Un amplio espectro de rasgos tratables existe en la bronquiectasia, abarcando factores como la infección, la inflamación, la hipersecreción de moco y las comorbilidades.
- Estos rasgos varían significativamente entre individuos, lo que subraya la necesidad de un manejo personalizado.
- La identificación de rasgos específicos permite intervenciones dirigidas, mejorando potencialmente los resultados de los pacientes.
Conclusiones:
- Los rasgos tratables en la bronquiectasia son diversos y están directamente relacionados con la heterogeneidad del paciente.
- Reconocer y abordar estos rasgos individuales es crucial para guiar la atención personalizada.
- La identificación y el manejo efectivos de los rasgos tratables pueden mejorar los resultados clínicos y optimizar la asignación de recursos en entornos del mundo real.
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