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Video Experimental Relacionado

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Manifestaciones Clínicas

See Ann Soo1, Jermyn Z See1, Nav Vij1

  • 1Neurowyzr Pte Ltd, Singapore, Singapore, Singapore.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
Resumen
Este resumen es generado por máquina.

La Prueba Digital de Función Cerebral (DBFS) demuestra una sólida validez de constructo y una alta fiabilidad test-retest en comparación con la MoCA para detectar el deterioro cognitivo leve. Esto establece la DBFS como una herramienta fiable para el seguimiento del deterioro cognitivo.

Palabras clave:
Prueba Digital de Función CerebralDeterioro Cognitivo LeveValidez de ConstructoFiabilidad Test-RetestMoCAEvaluación Cognitiva

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Área de la Ciencia:

  • Neurociencia
  • Tecnología Médica
  • Ciencia Cognitiva

Sus antecedentes:

  • La Prueba Digital de Función Cerebral (DBFS) es una herramienta digital para la detección temprana y el seguimiento del Deterioro Cognitivo Leve (MCI).
  • Si bien es comparable a la MoCA, la DBFS carecía de una validación formal de su validez de constructo y fiabilidad test-retest.
  • Este estudio tuvo como objetivo establecer estas propiedades psicométricas para la DBFS.

Objetivo del estudio:

  • Evaluar la validez de constructo de la DBFS frente a la MoCA.
  • Evaluar la fiabilidad test-retest de la DBFS.
  • Confirmar la DBFS como una herramienta válida y fiable para la evaluación cognitiva.

Principales métodos:

  • 157 individuos (de 10 a 81 años) se sometieron a evaluaciones de la DBFS y la MoCA.
  • 36 participantes completaron una segunda evaluación de la DBFS después de un intervalo mediano de 305 días.
  • La validez de constructo y la fiabilidad test-retest se analizaron utilizando correlaciones de rangos de Spearman parciales, controlando la edad, el sexo y la educación.

Principales resultados:

  • Las puntuaciones totales de la DBFS se correlacionaron significativamente con las puntuaciones totales de la MoCA (p < 0,001).
  • Se encontraron fuertes correlaciones positivas entre los dominios correspondientes de la DBFS y la MoCA (p < 0,05), lo que indica una buena validez de constructo.
  • La fiabilidad test-retest de la DBFS fue alta, con una ρ de Spearman = 0,65 (p < 0,001).

Conclusiones:

  • La DBFS mide eficazmente los constructos cognitivos previstos y muestra una alta fiabilidad a lo largo del tiempo.
  • Los hallazgos validan la DBFS como una herramienta práctica, escalable y eficiente para detectar y monitorizar el deterioro cognitivo temprano.
  • La DBFS es adecuada para su implementación en diversos entornos sanitarios para el cribado cognitivo.