Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

6.8K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
6.8K
Genomics02:02

Genomics

39.5K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
39.5K
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

15.2K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
15.2K
What is Population Genetics?01:25

What is Population Genetics?

64.3K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
64.3K
Comparing Copy Number Variations and SNPs02:26

Comparing Copy Number Variations and SNPs

18.5K
Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...
18.5K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

3.2K
3.2K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Biosynthetic gene clusters in <i>Pseudomonas viridiflava</i> have a fitness cost during <i>Arabidopsis thaliana</i> infection.

mSystems·2026
Same author

Teosinte alleles enhance nitrogen assimilation and seed protein in maize.

Nature·2026
Same author

Characterizing the genomic consequence of diploid-to-haploid induction in potato using large-scale whole-genome sequencing.

The Plant journal : for cell and molecular biology·2026
Same author

Rapid adaptation and extinction in synchronized outdoor evolution experiments of <i>Arabidopsis</i>.

Science (New York, N.Y.)·2026
Same author

Beyond Mendel: a call to revisit the genotype-phenotype map through new experimental paradigms.

Genetics·2026
Same author

Cell-type-specific gating of gene regulatory modules as a hallmark of early immune responses in Arabidopsis leaves.

The New phytologist·2026

Video Experimental Relacionado

Updated: Jan 7, 2026

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.7K

Complejidad bienvenida: grafos de pangenoma para genómica poblacional integral

Zhigui Bao1, Detlef Weigel1,2

  • 1Department of Molecular Biology, Max Planck Institute for Biology Tübingen, 72076 Tübingen, Germany.

Quantitative plant biology
|December 25, 2025
PubMed
Resumen

Los grafos de pangenoma capturan secuencias genómicas diversas más allá de las referencias lineales, avanzando en la genómica evolutiva y poblacional. Se necesita más innovación para genomas complejos e integración de datos.

Palabras clave:
variación complejagrafos de pangenomagenómica vegetal

Más Videos Relacionados

Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance
04:58

Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance

Published on: December 13, 2024

3.9K
Author Spotlight: A Cost-Effective Genomic Workflow for Advancing Rabies Control in Resource-Limited Settings
10:26

Author Spotlight: A Cost-Effective Genomic Workflow for Advancing Rabies Control in Resource-Limited Settings

Published on: August 18, 2023

6.8K

Videos de Experimentos Relacionados

Last Updated: Jan 7, 2026

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.7K
Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance
04:58

Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance

Published on: December 13, 2024

3.9K
Author Spotlight: A Cost-Effective Genomic Workflow for Advancing Rabies Control in Resource-Limited Settings
10:26

Author Spotlight: A Cost-Effective Genomic Workflow for Advancing Rabies Control in Resource-Limited Settings

Published on: August 18, 2023

6.8K

Área de la Ciencia:

  • Genómica
  • Biología Evolutiva
  • Bioinformática

Sus antecedentes:

  • Los genomas de referencia lineales limitan la representación de la diversidad de secuencias.
  • Los grafos de pangenoma ofrecen un enfoque más integral de la variación genómica.

Objetivo del estudio:

  • Revisar la progresión y el estado actual de las metodologías de grafos de pangenoma.
  • Identificar desafíos y direcciones futuras en las aplicaciones de grafos de pangenoma.

Principales métodos:

  • Revisión de la construcción de grafos de pangenoma aumentados con referencia y basados en ensamblaje.
  • Examen de las aplicaciones de genotipado y genómica funcional (transcriptómica, epigenómica).

Principales resultados:

  • Los grafos de pangenoma capturan variaciones estructurales complejas con sesgo reducido.
  • Los genomas de plantas presentan desafíos únicos que requieren innovación metodológica.
  • Los cuellos de botella incluyen la visualización, la escalabilidad y la integración de datos multiómicos.

Conclusiones:

  • Los esfuerzos impulsados por la comunidad son cruciales para unificar la construcción de grafos, el genotipado y la interpretación.
  • Los grafos de pangenoma proporcionan una base para una genómica poblacional y evolutiva más inclusiva.