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Updated: Jan 7, 2026

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Modeling the Functional Network for Spatial Navigation in the Human Brain
Published on: October 13, 2023
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Un mapa de la red funcional cortical que media la navegación naturalista
Tianjiao Zhang1,2, Emily X Meschke2, Jack L Gallant1,2
1Helen Wills Neuroscience Institute, University of California, Berkeley; Berkeley, CA 94720, USA.
bioRxiv : the preprint server for biology
|December 25, 2025
Resumen
La navegación en el mundo real implica percepción, planificación y acción. Este estudio mapeó el cerebro
Área de la Ciencia:
- Neurociencia
- Ciencia Cognitiva
Sus antecedentes:
- La navegación en el mundo real integra la percepción, la planificación y las acciones motoras.
- Estudios previos sugieren una amplia participación cortical, pero carecen de una caracterización detallada de las regiones parietales y prefrontales.
- Comprender la red de navegación completa es crucial para la neurociencia cognitiva.
Objetivo del estudio:
- Mapear y caracterizar la red cortical completa que apoya la navegación naturalista.
- Investigar las propiedades funcionales y la organización de las regiones cerebrales relacionadas con la navegación.
- Proporcionar una descripción unificada de la base neural de la navegación activa.
Principales métodos:
- Se utilizó la imagen por resonancia magnética funcional (fMRI) para registrar la actividad cerebral durante una tarea de navegación naturalista.
- Se ajustaron modelos de codificación de alta dimensionalidad utilizando regresión de cresta en banda para analizar 28.134 características.
- Se analizaron los datos de actividad cerebral para identificar regiones corticales funcionalmente distintas involucradas en la navegación.
Principales resultados:
- Una red de 11 regiones corticales funcionalmente distintas apoya la navegación naturalista.
- Esta red incluye cinco regiones prefrontales, tres parietales y tres de la corteza visual.
- El análisis del modelo de codificación reveló una transformación de las entradas perceptuales a las salidas de acción en estas regiones, organizadas a lo largo de gradientes funcionales.
Conclusiones:
- El estudio identificó una red cortical integral para la navegación en el mundo real.
- Estas 11 regiones están organizadas para procesar información desde la percepción hasta la toma de decisiones y la acción.
- Los hallazgos ofrecen una visión unificada de la organización de la red de navegación y proporcionan objetivos para futuras investigaciones.
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