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Manifestaciones Clínicas

Stephanie Tran1, Niyatee Samudra2

  • 1Stanford, Palo Alto, CA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
Resumen
Este resumen es generado por máquina.

Los EEG ambulatorios pueden detectar convulsiones sutiles en enfermedades neurodegenerativas, lo que ayuda en el diagnóstico y el manejo. Este estudio analiza su utilidad en pacientes con deterioro cognitivo leve o demencia.

Palabras clave:
EEG ambulatorioenfermedades neurodegenerativasconvulsiones sutilesdeterioro cognitivo levedemenciadiagnósticomanejo

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Área de la Ciencia:

  • Neurología
  • Neurociencia
  • Diagnóstico Médico

Sus antecedentes:

  • Las convulsiones sutiles y las descargas epileptiformes son comunes en las enfermedades neurodegenerativas.
  • Los pacientes con trastornos neurodegenerativos a menudo experimentan fluctuaciones cognitivas inexplicables.
  • Los electroencefalogramas (EEG) ambulatorios ofrecen monitoreo prolongado, lo que aumenta la tasa de detección de anomalías epileptiformes.

Objetivo del estudio:

  • Evaluar el rendimiento diagnóstico y el impacto clínico de los EEG ambulatorios en pacientes mayores de 45 años con deterioro cognitivo leve (MCI) o demencia.
  • Identificar predictores de anomalías epileptiformes en el EEG ambulatorio en esta población.
  • Evaluar si los hallazgos del EEG ambulatorio cambian el manejo clínico.

Principales métodos:

  • Análisis retrospectivo de aproximadamente 450 estudios de EEG ambulatorio realizados entre enero de 2023 y diciembre de 2024.
  • Criterios de inclusión: pacientes mayores de 45 años con diagnóstico de MCI o demencia.
  • Los datos extraídos incluyeron indicaciones para el EEG, duración, anomalías y cambios en el manejo; se evaluaron los predictores de anomalías y el impacto en el manejo.

Principales resultados:

  • El estudio se espera que arroje datos valiosos sobre la efectividad del EEG ambulatorio en la detección de anomalías epileptiformes en enfermedades neurodegenerativas.
  • Los resultados informarán sobre la utilidad del monitoreo prolongado de EEG en pacientes con deterioro cognitivo.

Conclusiones:

  • Los hallazgos pueden ayudar a establecer pautas para el uso de EEG ambulatorios en pacientes con enfermedades neurodegenerativas, especialmente aquellos con cognición fluctuante.
  • Aclarar las indicaciones para el EEG prolongado puede mejorar la precisión diagnóstica y la atención al paciente.