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Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
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Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
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Manifestaciones Clínicas

Riccardo Manca1,2, Annalena Venneri3,4

  • 1Brunel University London, Uxbridge, Middlesex, United Kingdom.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
Resumen
Este resumen es generado por máquina.

Los adultos mayores de minorías sexuales experimentan una peor salud mental y cognitiva subjetiva, pero un rendimiento cognitivo objetivo similar en comparación con los adultos mayores heterosexuales. El estrés de minoría impacta negativamente en su salud cognitiva, mientras que ser abierto sobre la orientación sexual ofrece protección.

Palabras clave:
adultos mayores de minorías sexualesestrés de minoríasalud cognitivaresilienciaorientación sexual

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Área de la Ciencia:

  • Gerontología; Psicología; Neurociencia

Sus antecedentes:

  • Las minorías sexuales exhiben disparidades en la salud, pero los factores de riesgo/protectores de la salud cognitiva siguen siendo poco estudiados.
  • Los adultos mayores que se identifican como no heterosexuales (adultos mayores de minorías sexuales, AMMS) enfrentan desafíos únicos que afectan su bienestar.
  • La investigación de factores psicosociales es crucial para comprender la salud cognitiva en los AMMS.

Objetivo del estudio:

  • Cuantificar el impacto de los factores psicosociales en la salud cognitiva de los AMMS.
  • Comparar la salud cognitiva entre AMMS y adultos mayores heterosexuales (AMH).
  • Identificar los factores de riesgo y protectores para el declive cognitivo en AMMS.

Principales métodos:

  • Encuestas en línea evaluaron riesgos psicosociales, declive cognitivo subjetivo (DCS) y creencias sobre la memoria en 39 AMMS y 30 AMH.
  • Los AMMS completaron medidas de estrés de minoría y apertura.
  • Se realizaron pruebas neuropsicológicas para evaluar el rendimiento cognitivo objetivo en un subconjunto de participantes.

Principales resultados:

  • Los adultos mayores de minorías sexuales (AMMS) reportaron peor salud mental, declive cognitivo subjetivo (DCS) y preocupaciones sobre la memoria que los adultos mayores heterosexuales (AMH), pero un rendimiento cognitivo objetivo similar.
  • La ansiedad se relacionó con una peor función atencional (Prueba de Trail Making) en los AMMS.
  • El estrés de minoría se correlacionó con un mayor riesgo de DCS del lenguaje y creencias negativas sobre la memoria; la apertura se asoció con una mejor memoria a corto plazo.

Conclusiones:

  • Los AMMS se ven afectados desproporcionadamente por la ansiedad relacionada con la función atencional en comparación con los AMH.
  • El estrés de minoría afecta negativamente la salud cognitiva subjetiva de los AMMS, mientras que la apertura actúa como un factor protector.
  • Se necesita más investigación para rastrear los cambios cognitivos y desarrollar estrategias de prevención para los AMMS.