Video Experimental Relacionado

Updated: Jan 7, 2026

The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions

The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions

Published on: February 1, 2018

Determinación de beta-lactoglobulina en alimentos mediante un aptasensor a base de papel colorimétrico utilizando MOF

Jingyi Yang¹, Wenli Shi¹, Xiangyang Liu¹

¹State Key Laboratory for Food Nutrition and Safety, College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China.

|December 25, 2025

Abstract:

This study developed a paper-based colorimetric aptasensor for the detection of β-lactoglobulin (β-LG) in foods, using copper‑cobalt metal-organic framework (CuCo-MOF) as the core catalyst. The sensor achieved a detection limit as low as 0.102 mg/L. and a wide linear range (0.39-1250 mg/L). It offered a simple detection procedure with less than 20 min detection time, making it more suitable for on-site food safety screening. Validation with commercial ELISA confirmed its suitability for analyzing real-food samples, such as milk and infant formula. The developed paper-based RGB colorimetric aptasensor emerges as a user-friendly and economical assay for high-throughput, visual, and accurate determination of β-LG in foods.

Palabras clave:

MOF aptasensor β-lactoglobulina

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