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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
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Manifestaciones Clínicas
Gabriela Raquel Paz Rivas1, Barbara Loeblein Uebel2, Victória Tizeli Souza3
1Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
Resumen
El deterioro cognitivo subjetivo (DCS) en personas sin deterioro cognitivo se relaciona con la ansiedad, no directamente con la calidad del sueño. La mala calidad del sueño en este grupo se correlaciona con niveles más altos de ansiedad, lo que sugiere una relación compleja.
Área de la Ciencia:
- Neurociencia; Gerontología; Medicina del Sueño
Sus antecedentes:
- El deterioro cognitivo subjetivo (DCS) representa un deterioro cognitivo autoperceptivo en individuos cognitivamente sanos (CS).; El DCS es un indicador temprano en el continuo de la enfermedad neurodegenerativa, con una etiología heterogénea y no completamente comprendida.; Las alteraciones del sueño se implican cada vez más en las quejas cognitivas y el deterioro cognitivo objetivo.
Objetivo del estudio:
- Investigar las quejas relacionadas con el sueño en personas con DCS.; Evaluar la asociación entre la calidad del sueño y las medidas cognitivas/neuropsiquiátricas en una cohorte del sur de Brasil.
Principales métodos:
- Se incluyeron individuos CS mayores de 65 años de la cohorte BRASCODE con quejas cognitivas subjetivas.; Se utilizaron evaluaciones neurocognitivas y neuropsiquiátricas, incluyendo la Escala de Quejas de Memoria (MCS), la Escala de Deterioro Cognitivo Subjetivo (SCD-S), el MMSE, el GAI, el GDS, el PSQI, el MBI y el NPI.; Se analizaron las correlaciones entre la calidad del sueño (PSQI) y las escalas cognitivas/de ansiedad/depresión/conductuales en el seguimiento a los 12 meses.
Principales resultados:
- Se encontró una correlación positiva significativa entre las puntuaciones del Índice de Calidad del Sueño de Pittsburgh (PSQI) y el Inventario de Gerontológico de Ansiedad (GAI) (p=0,01, rho=0,25).; No se observaron asociaciones significativas entre el PSQI y las escalas de DCS, MMSE, edad, educación o escalas conductuales (MBI, NPI).; La cohorte estuvo compuesta por 100 participantes (75% mujeres, mediana de edad 71).
Conclusiones:
- La mala calidad del sueño en individuos CS con DCS de una cohorte del sur de Brasil se asocia con la ansiedad.; Se necesita más investigación para dilucidar las intrincadas relaciones entre la cognición, la ansiedad y las alteraciones del sueño.; Los hallazgos resaltan la importancia de evaluar la ansiedad en individuos con DCS y quejas de sueño.
Palabras clave:
deterioro cognitivo subjetivoansiedadcalidad del sueñoadultos mayoresestudios de cohortesMás Videos Relacionados
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