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Manifestaciones Clínicas

Nancy X Chen1, Rachel Peterson2, M Maria Glymour3

  • 1University of California, Davis, Davis, CA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
Resumen
Este resumen es generado por máquina.

Los determinantes sociales de la salud, incluido el capital financiero, social y cultural a lo largo de la vida, impactan significativamente el deterioro cognitivo subjetivo (DCS). Abordar las inequidades socioeconómicas es crucial para mitigar el DCS y prevenir el deterioro cognitivo.

Palabras clave:
Deterioro cognitivo subjetivoEstatus socioeconómicoCapital financieroCapital socialCapital culturalDeterminantes sociales de la saludEnvejecimientoDemencia

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Área de la Ciencia:

  • Gerontología
  • Salud Pública
  • Ciencias Cognitivas

Sus antecedentes:

  • Los determinantes sociales de la salud (SDOH) son condiciones que afectan la salud desde el nacimiento hasta la vejez.
  • Investigaciones previas sugieren que los SDOH pueden influir en el deterioro cognitivo subjetivo (DCS), un factor de riesgo de demencia.

Objetivo del estudio:

  • Examinar la asociación entre el estatus socioeconómico (SES) a lo largo de la vida y el DCS.
  • Investigar cómo el capital financiero, cultural y social a lo largo de la vida se relaciona con el deterioro cognitivo.

Principales métodos:

  • Se utilizaron dos cohortes multieiénicas de miembros de planes de salud a largo plazo sin diagnósticos previos de demencia.
  • Se construyeron variables de SES a lo largo de la vida que miden los dominios financiero, cultural y social basándose en calificaciones de la niñez y actuales.
  • Se evaluó el DCS utilizando la escala de Cognición Cotidiana (ECog) y se analizaron las asociaciones utilizando modelos de regresión lineal multivariable.

Principales resultados:

  • La baja capital financiero, social y cultural en la niñez y en la vida tardía se asociaron con calificaciones más altas de DCS.
  • En modelos combinados, estos factores del SES siguieron estando significativamente relacionados con una peor función cognitiva (puntuaciones ECog).

Conclusiones:

  • El capital financiero, social y cultural a lo largo de la vida moldea críticamente el DCS.
  • Los hallazgos resaltan la necesidad de abordar las disparidades socioeconómicas en el acceso a los recursos para mitigar el riesgo de DCS y deterioro cognitivo.