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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
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Manifestaciones Clínicas
Dylan X Guan1, Byron Creese2, Cassandra M Germain3
1Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
Resumen
La agitación en los trastornos neurocognitivos es difícil de medir de manera consistente. Pocas escalas validadas se alinean completamente con los criterios de la Asociación Internacional de Psicogeriatría (IPA), lo que afecta la investigación y la práctica clínica.
Área de la Ciencia:
- Psiquiatría Geriátrica
- Neurociencia
- Psicología Clínica
Sus antecedentes:
- La agitación es un comportamiento común y angustiante en los trastornos neurocognitivos.
- La medición de la agitación se complica por definiciones y herramientas inconsistentes.
- La Asociación Internacional de Psicogeriatría (IPA) estableció criterios de consenso para la agitación.
Objetivo del estudio:
- Revisar sistemáticamente las escalas de agitación validadas en adultos mayores con trastornos neurocognitivos.
- Evaluar la alineación de estas escalas con los criterios de la IPA.
Principales métodos:
- Revisión sistemática de las bases de datos MEDLINE, EMBASE y PsycINFO.
- Se incluyeron estudios de validación de escalas de agitación en poblaciones con trastornos neurocognitivos.
- La alineación de las escalas con los criterios de la IPA fue evaluada por revisores independientes.
Principales resultados:
- Se identificaron 39 escalas de agitación únicas de 226 artículos de texto completo.
- La Escala de Observación del Personal sobre Agresividad (Staff Observation Aggression Scale), el Inventario Neuropsiquiátrico para Hogares de Ancianos (Neuropsychiatric Inventory Nursing Home) y la Escala Modificada de Agresión Abierta (Modified Overt Aggression Scale) mostraron la mayor alineación con la IPA.
- Muchas escalas carecían de ítems sobre actividad motora excesiva o agresión física.
Conclusiones:
- Aunque existen numerosas escalas de agitación para adultos mayores, pocas cumplen completamente los criterios de la IPA.
- Las deficiencias comunes incluyen la captura inadecuada de la persistencia de los síntomas y la angustia emocional.
- Existe una variación significativa en cómo las escalas abordan los dominios centrales de la agitación.
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