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Manifestaciones Clínicas

Tzung-Jeng Hwang1, Cho-Hsiang Yang2, Yi-Ting Lin3

  • 1National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
Resumen
Este resumen es generado por máquina.

Los síntomas neuropsiquiátricos pueden predecir el deterioro cognitivo. Las calificaciones de la Lista de Verificación de Deterioro Conductual Leve (MBI-C) difieren según quién proporciona la información (uno mismo, un informante o un investigador), lo que afecta las evaluaciones de afecciones como el Deterioro Conductual Leve (MBI).

Palabras clave:
Deterioro conductual leveDeterioro cognitivoEvaluación neuropsiquiátricaLista de verificación de deterioro conductual leveSíntomas neuropsiquiátricos

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Área de la Ciencia:

  • Gerontología; Neurociencia; Psiquiatría

Sus antecedentes:

  • Los síntomas neuropsiquiátricos son posibles indicadores tempranos de deterioro cognitivo y demencia.; La Lista de Verificación de Deterioro Conductual Leve (MBI-C) evalúa los cambios neuropsiquiátricos, pero puede estar sujeta a sesgos de calificación.; Pueden surgir discrepancias en las calificaciones del MBI-C de diferentes fuentes de información.

Objetivo del estudio:

  • Investigar las diferencias en las calificaciones de la Lista de Verificación de Deterioro Conductual Leve (MBI-C) entre autoinformes, informes de informantes y evaluaciones de investigadores.; Determinar si las perspectivas de los encuestados influyen en las puntuaciones del MBI-C en personas con deterioro cognitivo o en riesgo de padecerlo.

Principales métodos:

  • Se reclutaron 123 participantes con Deterioro Conductual Leve (MBI), incluidos aquellos con MBI puro y aquellos con MBI y deterioro cognitivo leve (MCI).; Los participantes, sus informantes e investigadores completaron el MBI-C.; Las evaluaciones de los investigadores, basadas en datos de los participantes e informantes, sirvieron como el estándar de oro para la identificación del MBI.

Principales resultados:

  • Se encontraron diferencias significativas en las puntuaciones del MBI-C entre las calificaciones de autoevaluación, informante e investigador en los dominios de disminución de la motivación, desregulación afectiva e inapropiado social.; Las calificaciones de autoevaluación e investigador fueron más altas para la disminución de la motivación en comparación con las calificaciones de los informantes.; Las calificaciones de los investigadores fueron más altas para la desregulación afectiva que las calificaciones de los informantes, mientras que las calificaciones de los informantes fueron más altas para el inapropiado social que las autocalificaciones.

Conclusiones:

  • Las perspectivas de los encuestados influyen significativamente en las puntuaciones de la Lista de Verificación de Deterioro Conductual Leve (MBI-C).; Los médicos deben considerar las posibles discrepancias entre las calificaciones de autoevaluación, informante e investigador al interpretar los resultados del MBI-C.; Se recomienda precaución al utilizar datos del MBI-C de diversas fuentes para diagnosticar o monitorear el deterioro cognitivo.