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Manifestaciones Clínicas

Satyam Chauhan1, Ikran Dahir2, Veena Kumari2

  • 1Brunel University of London, London, Uxbridge, United Kingdom.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
Resumen
Este resumen es generado por máquina.

El deterioro cognitivo subjetivo (SCI, por sus siglas en inglés) media parcialmente el vínculo entre los síntomas de psicosis y las alteraciones del sueño en adultos mayores. La identificación temprana de problemas de sueño y trastornos relacionados puede ayudar a prevenir el deterioro cognitivo.

Palabras clave:
adultos mayorespsicosisdeterioro cognitivo subjetivoalteraciones del sueñoneurocienciagerontologíapsiquiatría

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Área de la Ciencia:

  • Neurociencia
  • Gerontología
  • Psiquiatría

Sus antecedentes:

  • Las alteraciones del sueño afectan al 50% de los adultos mayores, y están relacionadas con la psicosis y la demencia.
  • El papel del deterioro cognitivo subjetivo (SCI) en las relaciones psicosis-sueño no está claro.
  • Se investigaron los síntomas de psicosis, el SCI y las facetas del sueño en 14.846 adultos mayores del Reino Unido.

Objetivo del estudio:

  • Examinar el impacto de los síntomas de psicosis en el sueño.
  • Determinar si el SCI media la relación entre los síntomas de psicosis y el sueño.
  • Analizar las facetas del sueño, incluida la fragmentación, la duración, la calidad y el sueño profundo.

Principales métodos:

  • Medidas de autoinforme en línea para el sueño, los síntomas de psicosis y el SCI.
  • Regresión lineal para analizar las relaciones psicosis-sueño.
  • Análisis de mediación para evaluar el papel mediador del SCI.

Principales resultados:

  • Los síntomas de psicosis, el SCI y las facetas del sueño mostraron correlaciones significativas.
  • El SCI medió parcialmente la relación psicosis-sueño.
  • Después de controlar las covariables, el SCI medió completamente el sueño profundo, la fragmentación, la inercia, la calidad y el mantenimiento, y medió parcialmente el inicio y la duración del sueño.

Conclusiones:

  • Las alteraciones del sueño están relacionadas con los síntomas de psicosis y el SCI en adultos mayores.
  • El SCI juega un papel mediador importante en la relación psicosis-sueño.
  • La identificación temprana de problemas de sueño y comorbilidades es crucial para prevenir el deterioro cognitivo y la demencia.