Jove
Visualize
Contáctanos

Videos de Conceptos Relacionados

Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

520
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
520
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

299
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
299
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

364
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
364
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

436
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
436
Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

652
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
652
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

437
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
437

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Music as a scientific metaphor for mind and brain.

Neuroscience and biobehavioral reviews·2026
Same author

Correction: The role of brain health and resilience in reshaping trajectories of late-life neuropsychiatric disorders.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2026
Same author

Evaluation of perception towards brain health in Nigeria: Results from a nationwide awareness survey.

Journal of public health in Africa·2026
Same author

Sociodemographic variables as predictors of antidepressant treatment outcome in major depressive disorder.

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)·2026
Same author

Association of apolipoprotein E variants on Alzheimer's disease in Latin America: A systematic review and meta-analysis.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Plasma ATN biomarkers across the alzheimer's disease continuum in a Chilean community- and clinic-based cohort.

Alzheimer's research & therapy·2026
Same journal

Unveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Estimated labor market outcomes of people progressing from preclinical to early-stage Alzheimer's disease in the United States.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Amyloid exacerbates tau and alpha-synuclein pathologies, behavioral impairments, and neuroinflammation in a mixed dementia model.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Multimorbidity burden and patterns associated with DeepBrainNet-derived brain-age gap in dementia-free older adults: A community-based study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Reply to "Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities".

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Ver todos los artículos relacionados
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Video Experimental Relacionado

Updated: Jan 7, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.4K

Manifestaciones Clínicas

Mario A A Parra1, Martin Alejandro Bruno2,3,4, Claudia Duran-Aniotz5

  • 1University of Strathcylde, Glasgow, Glasgow, United Kingdom.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
Resumen
Este resumen es generado por máquina.

Las pruebas cognitivas, incluida la Prueba de Unión de Memoria a Corto Plazo Visual (VSTMBT), detectan con precisión la demencia por enfermedad de Alzheimer (DEA) en seis países latinoamericanos. Una puntuación compuesta de tres pruebas mostró una alta precisión diagnóstica, lo que respalda la validez transcultural.

Palabras clave:
pruebas cognitivasdemencia por enfermedad de AlzheimerAmérica Latinavalidez transculturalVSTMBTCS21TCBFT

Más Videos Relacionados

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.7K
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

6.1K

Videos de Experimentos Relacionados

Last Updated: Jan 7, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.4K
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.7K
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

6.1K

Área de la Ciencia:

  • Neurociencia
  • Psicología
  • Investigación transcultural

Sus antecedentes:

  • El diagnóstico de demencia por enfermedad de Alzheimer (DEA) se basa en el deterioro cognitivo, pero las evaluaciones actuales carecen de precisión y están influenciadas culturalmente.
  • El juicio clínico es vital cuando los biomarcadores no están disponibles o entran en conflicto con los hallazgos clínicos.
  • La armonización transcultural de las herramientas de diagnóstico es necesaria para la precisión global.

Objetivo del estudio:

  • Evaluar la validez transcultural de la Prueba de Unión de Memoria a Corto Plazo Visual (VSTMBT) y otras evaluaciones cognitivas en América Latina.
  • Determinar si estas pruebas pueden detectar de manera confiable la demencia por enfermedad de Alzheimer (DEA) en diversos contextos culturales.

Principales métodos:

  • Se reclutaron 426 pacientes con DEA y 869 controles sanos de Argentina, Brasil, Chile, Colombia, México y Perú.
  • Se administró un protocolo integral que incluye el VSTMBT, la Prueba de la Historia de Craft 21 (CS21T) y la Prueba de la Figura Compleja de Benson (CBFT).
  • Se emplearon Modelos Lineales Generales (GLM) y análisis de la Curva Característica de Operación del Receptor (ROC) para evaluar las diferencias entre grupos y la precisión de la clasificación, controlando los factores de confusión.

Principales resultados:

  • El VSTMBT mostró déficits significativos en pacientes con DEA, particularmente en la unión forma-color.
  • Las tres pruebas (VSTMBT, CS21T, CBFT) revelaron déficits cognitivos significativos en individuos con DEA en comparación con controles sanos en todos los países.
  • Una puntuación compuesta que combina las tres pruebas demostró una alta precisión de clasificación (AUC > 0.78) para la detección de DEA en los países latinoamericanos estudiados.

Conclusiones:

  • El VSTMBT, el CS21T y el CBFT son herramientas confiables para evaluar la DEA en diversas poblaciones latinoamericanas.
  • A pesar de la variabilidad observada, estas pruebas identificaron consistentemente déficits significativos relacionados con la DEA, independientemente de los factores de confusión.
  • Los hallazgos respaldan la validez transcultural del VSTMBT en América Latina, extendiendo hallazgos previos de países europeos.