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Updated: Jan 7, 2026

Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development
Published on: April 15, 2013
Radicales Orgánicos para Terapia Tumoral
1State Key Laboratory of Coordination Chemistry, MOE Key Laboratory of Mesoscopic Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, P. R. China.
Abstract:
Organic radical materials have emerged as promising candidates for tumor therapy, owing to their distinctive open-shell electronic structures and superior photophysical characteristics. Through chemical modifications and nanotechnological approaches, these materials have paved the way for precision medicine, showcasing robust spin-coupling phenomena and near-infrared light absorption properties. Leveraging these attributes, organic radicals have demonstrated enhanced therapeutic outcomes in photothermal therapy, photodynamic therapy, and other novel modalities. This review provides an overview of the applications of organic radicals in tumor therapy and also highlights existing hurdles and future prospects of organic radicals in cancer treatment.
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