Jove
Visualize
Contáctanos

Videos de Conceptos Relacionados

Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

520
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
520
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

299
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
299
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

364
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
364
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

436
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
436
Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

652
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
652
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

437
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
437

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Baseline characteristics of the SINgapore GERiatric Intervention Study to Reduce Cognitive Decline and Physical Frailty (SINGER) multidomain dementia prevention randomized controlled trial and insights from the recruitment process.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Posterior Cortical Atrophy in the Asia-Pacific: A Report From the PCA Asian Workgroup.

Annals of clinical and translational neurology·2026
Same author

ReCOGnAIze app to detect vascular cognitive impairment and mild cognitive impairment.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Cerebral haemodynamics and white matter hyperintensities: findings using non-invasive brain imaging.

The journal of prevention of Alzheimer's disease·2026
Same author

A regional framework for the detection and management of ARIA with anti-amyloid therapies in early Alzheimer's disease in Asia.

The journal of prevention of Alzheimer's disease·2026
Same author

Clinical Manifestations.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same journal

Multimorbidity burden and patterns associated with DeepBrainNet-derived brain-age gap in dementia-free older adults: A community-based study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Correlates and predictors of self-efficacy among dementia caregivers: D-CARE findings.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

What should convince a clinician of disease modification in Alzheimer's disease clinical trials?

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Primary cilia-extracellular vesicle crosstalk in Alzheimer's disease: Emerging mechanisms and biomarker potential.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Evidence for progressive neurodegeneration in iatrogenic cerebral amyloid angiopathy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Human brain connectome profiles mediate the relationship between pathology burden and clinical phenotypes in Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Ver todos los artículos relacionados
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Video Experimental Relacionado

Updated: Jan 7, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.4K

Manifestaciones Clínicas

Yi Jin Leow1, Pricilia Tanoto2, Nagaendran Kandiah3

  • 1nil, nil, nil, Nicaragua.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
PubMed
Resumen
Este resumen es generado por máquina.

Los síntomas de deterioro conductual leve (MBI), medidos por el MBI-Checklist (MBI-C), predicen el deterioro cognitivo. Abordar los síntomas de MBI ofrece oportunidades para la intervención temprana en la salud cognitiva.

Palabras clave:
Deterioro conductual leveDeterioro cognitivoMBI-ChecklistIntervención tempranaSalud cognitiva

Más Videos Relacionados

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.7K
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

6.1K

Videos de Experimentos Relacionados

Last Updated: Jan 7, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.4K
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.7K
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

6.1K

Área de la Ciencia:

  • Neurología
  • Gerontología
  • Psiquiatría

Sus antecedentes:

  • Los cambios conductuales sutiles pueden indicar un deterioro cognitivo temprano, ofreciendo oportunidades de intervención.
  • El Deterioro Conductual Leve (MBI) es un precursor reconocido del deterioro cognitivo y la enfermedad de Alzheimer (EA).
  • El MBI-Checklist (MBI-C) detecta eficazmente el MBI, pero su valor predictivo en poblaciones del sudeste asiático necesita exploración debido a la posible subnotificación cultural.

Objetivo del estudio:

  • Evaluar si las puntuaciones longitudinales del MBI-Checklist (MBI-C) predicen resultados cognitivos en una cohorte del sudeste asiático.
  • Evaluar la asociación entre los síntomas de MBI y el deterioro cognitivo posterior.
  • Identificar dominios de síntomas de MBI específicos que sean fuertes predictores del deterioro cognitivo.

Principales métodos:

  • Se evaluó a 571 participantes del estudio Biomarcers and Cognition Study, Singapur (BIOCIS), durante dos visitas, con un año de diferencia.
  • Los participantes se clasificaron según el estado cognitivo (normal, declive subjetivo, MCI, demencia).
  • Se utilizaron puntuaciones de MBI-C autoinformadas para medir los síntomas conductuales, y los resultados cognitivos longitudinales se analizaron utilizando modelos mixtos lineales.

Principales resultados:

  • Los participantes con puntuaciones clínicas de MBI-C mostraron un peor rendimiento cognitivo basal en múltiples dominios.
  • Las puntuaciones totales más altas de MBI-C en la Visita 1 predijeron significativamente peores diagnósticos cognitivos en la Visita 2.
  • La interacción Visita×MBI-C indicó una relación intensificada entre las puntuaciones de MBI-C y el deterioro cognitivo a lo largo del tiempo, con las 'Creencias Anormales' mostrando la asociación más fuerte.

Conclusiones:

  • Las puntuaciones de MBI-C autoinformadas son predictores significativos del deterioro cognitivo temprano, validando los síntomas de MBI como marcadores clínicos.
  • El impacto progresivo del MBI en la cognición es evidente a través de la asociación cada vez más fuerte con el tiempo.
  • El subdominio de 'Creencias Anormales' es un marcador particularmente fuerte de deterioro cognitivo, lo que resalta el papel del MBI en las estrategias de intervención temprana.