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Avances en las interfaces de adhesión de materiales de reparación de nervios periféricos: mecanismo, clasificación,

Qi Meng^1,2,3,4, Meng Zhang^1,2,3,4, Yichong Zhang^1,2,3,4

¹Department of Orthopedics and Trauma, Peking University People's Hospital, Beijing, China.

Frontiers in cell and developmental biology

|December 29, 2025

Resumen

La optimización de la interfaz de adhesión es crucial para materiales eficaces de reparación de nervios. Esta revisión detalla los mecanismos de adhesión y las estrategias de diseño para una mejor regeneración nerviosa y aplicación clínica.

Sus antecedentes:

La lesión del nervio periférico (LNP) presenta desafíos significativos para la recuperación funcional.
Los materiales de reparación nerviosa son críticos para abordar la LNP, siendo la adhesión de la interfaz un factor clave.
La comprensión de los mecanismos de adhesión es vital para avanzar en las estrategias terapéuticas de la LNP.

Conclusiones:

El diseño óptimo de la interfaz es esencial para mejorar la eficacia de los materiales de reparación nerviosa.
Centrarse en materiales de adhesión húmeda es crucial para la regeneración nerviosa *in vivo*.
Esta revisión proporciona una referencia para el desarrollo de materiales de reparación de LNP mejorados para la traslación clínica.

Palabras clave:

interfaz de adhesión funcionalización material de reparación nerviosa lesión del nervio periférico adhesión húmeda

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