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Video Experimental Relacionado

Updated: Jun 13, 2026

Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction

Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction

Published on: February 26, 2014

TransBrain: un marco computacional para traducir fenotipos cerebrales entre humanos y ratones

Shangzheng Huang^1,2, Tongyu Zhang^1,2, Changsheng Dong^1,2

¹State Key Laboratory of Cognitive Science and Mental Health, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.

|December 30, 2025

Resumen

Este resumen es generado por máquina.

TransBrain es un nuevo marco computacional para la traducción bidireccional de fenotipos cerebrales entre humanos y ratones. Esta herramienta mejora la investigación cerebral entre especies al mejorar el mapeo de homología y permitir investigaciones mecanicistas.

Palabras clave:

neurociencia computacional biología computacional genómica homología cerebral modelos de ratón fenotipos cerebrales investigación traslacional

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Sus antecedentes:

Quantitative cross-species brain research is limited by challenges in bridging preclinical rodent and human studies.
Existing methods lack accurate homology mapping between mouse and human brain structures.

Conclusiones:

TransBrain facilitates accurate, quantitative cross-species comparisons of brain function and organization.
The framework enables mechanistic investigation of normal and pathological brain functions across species.
TransBrain advances translational neuroscience by bridging the gap between preclinical models and human studies.