TransBrain: un marco computacional para traducir fenotipos cerebrales entre humanos y ratones

Sus antecedentes:

• Quantitative cross-species brain research is limited by challenges in bridging preclinical rodent and human studies.
• Existing methods lack accurate homology mapping between mouse and human brain structures.

Conclusiones:

• TransBrain facilitates accurate, quantitative cross-species comparisons of brain function and organization.
• The framework enables mechanistic investigation of normal and pathological brain functions across species.
• TransBrain advances translational neuroscience by bridging the gap between preclinical models and human studies.