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Updated: Jan 7, 2026

Noninvasive and Invasive Renal Hypoxia Monitoring in a Porcine Model of Hemorrhagic Shock

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Published on: October 28, 2022

Estudio de cohorte anal sobre la hipotensión intraoperatoria como factor de riesgo de lesión renal aguda

Vishal Mruthyunjaya Kalmani¹, Dhyaneshwar Ra², Yeruva Bheemeswara Reddy³

¹Department of Surgery, Barking Havering and Redbridge University Hospitals NHS Trust, Essex, United Kingdom.

|December 30, 2025

Abstract:

Acute kidney injury (AKI) is a serious complication that happens after surgery and intraoperative hypotension (IOH) is a modifiable risk factor. We did a cohort analytical study consisting of 145 adult patients who were undergoing major non-cardiac surgery under general anesthesia. Patients who were diagnosed with IOH (defined as mean arterial pressure <65 mmHg for ≥15 minutes), had significantly higher rates of postoperative AKI. Multivariate analysis confirmed independent predictors of AKI including IOH, chronic kidney disease, and prolonged operative time. Overall, this study highlights the importance of hemodynamic monitoring and the continuing maintenance of MAP ≥65 mmHg as a potential way to reduce renal complications.

Palabras clave:

Presión arterial media daño renal agudo estudios de cohortes analíticos hipotensión intraoperatoria riesgo perioperatorio

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