Granuloma Ulceroso Traumático Gingival con Eosinofilia Estromal (TUGSE) que Imita el Carcinoma

Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is an uncommon benign lesion of the oral mucosa that clinically resembles malignancy, often creating diagnostic concern. We report the case of a 46-year-old woman presenting with a persistent gingival growth in the posterior mandible. Clinical examination revealed a firm erythematous mass with a necrotic white plaque. Histopathology and immunohistochemistry confirmed TUGSE, and surgical excision led to complete healing without recurrence. This case highlights the importance of including TUGSE in the differential diagnosis of chronic oral ulcers and emphasizes early biopsy to avoid misdiagnosis, unnecessary aggressive treatment, and patient distress.