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Isquemia intestinal transitoria inducida por semaglutida: reporte de un caso

Pavan Kumar Reddy Kalluru, Apoorva Cherukuri, Deekshitha Kuchi

International journal of clinical pharmacology and therapeutics

|December 30, 2025

Abstract:

Obesity is a global health issue that impacts millions of people worldwide. Semaglutide is a glucagon-like peptide-1 receptor agonist that was initially developed as a treatment for type 2 diabetes mellitus under the brand name Ozempic. Additional studies showed semaglutide at larger doses (marketed as Wegovy) to be an effective medication for weight management. Wegovy for managing obesity is typically well tolerated; however, there have been reports of gastrointestinal adverse effects. Only 1 case of Wegovy-induced transient intestinal ischemia has been documented, making it extremely unusual. Here, we report the case of a 50-year-old man who experienced transient intestinal ischemia following his first Wegovy dosage.

Palabras clave:

semaglutida obesidad isquemia intestinal efectos adversos reporte de caso

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