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Miofibroma Esplénico Aislado en un Niño en PET/CT con 18F-FDG

Xingyi Wang^1,2,3, Yuhu Lv^1,2,3, Chunxia Qin^1,2,3

¹Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology.

Clinical nuclear medicine

|December 30, 2025

Abstract:

We present a rare case of an isolated splenic myofibroma in a child evaluated with 18F-FDG PET/CT. An 8-year-old boy underwent PET/CT for a left cervical mass, which incidentally revealed a splenic nodule (1.3×1.0 cm) with markedly increased 18F-FDG uptake (SUVmax=8.1). MRI showed an enhancing, low T2-weighted signal nodule without diffusion restriction. Histopathology after splenectomy confirmed myofibroma. Isolated myofibromas are rare benign spindle cell tumors in children and can demonstrate intense 18F-FDG uptake, mimicking malignancy. Awareness of this potential false-positive pitfall is essential in pediatric PET interpretation.

Palabras clave:

RM lesión esplénica aislada miofibroma

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