Eficacia de la Localización con Magseed para Lesiones Mamarias No Palpables: Una Revisión Sistemática y Metaanálisis

Accurate preoperative localization is essential for successful breast-conserving surgery on non-palpable breast lesions. In recent years, Magseed has emerged as a non-wired localization approach with promising outcomes due to its flexibility and precision. This meta-analysis aimed to evaluate the efficacy and safety of Magseed localization on non-palpable breast lesions.

Ovid MEDLINE, CINAHL, Ovid EMBASE, and The Cochrane Library were searched from inception to February 2025, following PRISMA guidelines. The pooled mean and proportions were analyzed using a random-effects model. The review was registered with PROSPERO (CRD420250654940).

From 958 studies screened, 16 studies involving 2,117 patients and 2,176 Magseeds were included. The overall rate of positive margins was 7.6% [95% confidence interval (CI)=0.04, 0.11, I²=88%], and the re-excision rate was 8.2% (95%CI=0.05, 0.12, I²=87%). The overall complication rate was 0.6% (95%CI=0.001, 0.011, I²=7%). The success rate for Magseed placement was 99.3% (95%CI=0.987, 0.998, I²=1%), the migration-related failure was 0.6% (95%CI=0.001, 0.011, I²=0%), and the retrieval success rate was 99.6% (95%CI=0.992, 0.999, I²=0%). The mean operative time was 61.4 min (95%CI=55.9, 66.9, I²=98%).

Magseed appears to be a safe and effective technique for the preoperative localization of selected non-palpable breast lesions. Nonetheless, further studies based on breast density, size, and depth are required to investigate the feasibility of preoperative Magseed localization for patients with non-palpable breast lesions.