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Serratia nevei en Nigeria: Primer Informe y Distribución Global
Ayodele Timilehin Adesoji1, Emmanuel Dayo Alabi1, Vittoria Mattioni Marchetti2
1Department of Microbiology, Federal University, Dutsin-Ma 821101, Katsina State, Nigeria.
Microorganisms
|December 31, 2025
Resumen
El primer aislamiento de Serratia nevei de muestras de alimentos nigerianos destaca su emergencia en la cadena de suministro de alimentos. El análisis genómico es crucial para la identificación precisa de especies de Serratia y la comprensión de los riesgos zoonóticos potenciales.
Área de la Ciencia:
- Microbiología
- Genómica
- Seguridad Alimentaria
Sus antecedentes:
- Las especies de Serratia son patógenos oportunistas con diversos orígenes ambientales.
- La identificación precisa de las especies de Serratia es un desafío utilizando métodos convencionales.
- La presencia de Serratia en la cadena de suministro de alimentos representa riesgos potenciales para la salud pública.
Objetivo del estudio:
- Informar sobre el primer aislamiento y caracterización de Serratia nevei a partir de muestras de alimentos en Nigeria.
- Investigar la resistencia a los antimicrobianos y los factores de virulencia de la cepa S. nevei identificada.
- Enfatizar la importancia de la secuenciación del genoma completo para la identificación precisa de especies dentro del género Serratia.
Principales métodos:
- Vigilancia epidemiológica y recolección de 180 muestras de alimentos de un mercado nigeriano.
- Aislamiento e identificación utilizando agar cromogénico y MicroScan autoSCAN-4.
- Pruebas de susceptibilidad antimicrobiana y secuenciación del genoma completo (WGS) para identificación definitiva y análisis genómico.
Principales resultados:
- La cepa F129B de Serratia nevei se aisló de una muestra de carne de res y se identificó erróneamente inicialmente por métodos estándar.
- La WGS confirmó el aislamiento como S. nevei, revelando resistencia a amoxicilina/ácido clavulánico, colistina, aztreonam y cefuroxima.
- El genoma albergaba genes de resistencia a beta-lactámicos, aminoglucósidos, fosfomicina, estreptomicina y tetraciclina, junto con factores de virulencia.
Conclusiones:
- La identificación precisa de las especies de Serratia requiere caracterización genómica debido a las limitaciones de los métodos fenotípicos.
- La aparición de S. nevei en la cadena de suministro de alimentos de Nigeria indica un potencial de transmisión zoonótica.
- Es fundamental una vigilancia mejorada de las cadenas de suministro de alimentos en el noroeste de Nigeria para monitorear patógenos emergentes.
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