Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

The Endoplasmic Reticulum01:43

The Endoplasmic Reticulum

20.9K
The endoplasmic reticulum or ER makes up for more than half of the membranes in a cell and accounts for 10% of total cell volume. It is also the primary protein and lipid synthesis factory for most cell organelles, such as the Golgi apparatus, lysosomes, secretory vesicles, and the plasma membrane. Despite being the most extensive and functionally complex subcellular organelle, ER was the last to be discovered. After years of deliberation, Keith Porter and George Palade in the year 1954,...
20.9K
Endoplasmic Reticulum01:39

Endoplasmic Reticulum

105.7K
The Endoplasmic Reticulum (ER) in eukaryotic cells is a substantial network of interconnected membranes with diverse functions, from calcium storage to biomolecule synthesis. A primary component of the endomembrane system, the ER manufactures phospholipids critical for membrane function throughout the cell. Additionally, the two distinct regions of the ER specialize in the manufacture of specific lipids and proteins.
105.7K
Assembly of the Lipid Bilayer in the ER01:28

Assembly of the Lipid Bilayer in the ER

4.0K
Biological membranes are more than just a barrier separating cell cytoplasm from the outside environment. They are highly dynamic and help maintain the integrity and physiological stability of the cells as well as membrane-bound organelles. Membranes also play vital roles in cell-to-cell and intracellular communication.
A large chunk of any biological membrane is composed of phospholipids. These lipids have a heterogeneous distribution across different subcellular organelles and even between...
4.0K
Golgi Apparatus01:49

Golgi Apparatus

99.7K
As they leave the Endoplasmic Reticulum (ER), properly folded and assembled proteins are selectively packaged into vesicles. These vesicles are transported by microtubule-based motor proteins and fuse together to form vesicular tubular clusters, subsequently arriving at the Golgi apparatus, a eukaryotic endomembrane organelle that often has a distinctive ribbon-like appearance.
99.7K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Sexual life cycle establishes the unicellular red algae Cyanidiophyceae as a genetically tractable model for eukaryotic evolution.

The Plant cell·2026
Same author

Cytoplasmic competition between separate parental pronuclei in zygotes.

Nature·2026
Same author

The 4.4 Å Capsid Structure of the Giant Melbournevirus Belonging to the <i>Marseilleviridae</i> Family.

Viruses·2026
Same author

Type III CD38 is present in the membrane of neurosecretory vesicles and has a cytosol-facing catalytic domain in primate oxytocin neurons.

Journal of neuroendocrinology·2026
Same author

Diterpene Molecular Glue Stabilizes Protein-Protein Interactions of a Disordered Phosphoprotein that Controls Translational Repression.

JACS Au·2026
Same author

Mechanical control of the insect extracellular matrix nanostructure.

Science advances·2026
Same journal

A pan-vertebrate signaling motif controls the molecular function of intracellular AQP12.

The Journal of cell biology·2026
Same journal

Synergistic assembly, disassembly, and protection of complex forms of bundled F-actin.

The Journal of cell biology·2026
Same journal

Recruitment and release of XPG during NER is controlled by pre- and post-incision factors and EXO1.

The Journal of cell biology·2026
Same journal

Meiotic CENP-C supports centromere assembly and kinetochore recruitment in spermatogenesis.

The Journal of cell biology·2026
Same journal

Phosphatidylserine and RhoB connect PI4P and PA metabolism to maintain plasma membrane identity.

The Journal of cell biology·2026
Same journal

PIKfyve influences inter-organelle contacts with lysosomes to modulate the endoplasmic reticulum.

The Journal of cell biology·2026
Ver todos los artículos relacionados

Video Experimental Relacionado

Updated: Jan 7, 2026

Visualization of Caenorhabditis elegans Cuticular Structures Using the Lipophilic Vital Dye DiI
08:22

Visualization of Caenorhabditis elegans Cuticular Structures Using the Lipophilic Vital Dye DiI

Published on: January 30, 2012

17.7K

Patrones del retículo endoplasmático en la nanoestructura de la cutícula de insectos

Sachi Inagaki1,2, Housei Wada1, Takeshi Itabashi3,4

  • 1Laboratory for Morphogenetic Signaling, RIKEN Center for Biosystems Dynamics Research , Kobe, Japan.

The Journal of cell biology
|December 31, 2025
PubMed
Resumen
Este resumen es generado por máquina.

Los investigadores descubrieron cómo se forman los nanoporos en la cutícula de los insectos mediante una novedosa interacción RE-membrana plasmática. Este proceso, que implica la RE-fagia, revela información sobre el nanopatterning de insectos y el control genético para aplicaciones biomiméticas.

Palabras clave:
nanoporoscutícula de insectosretículo endoplasmáticomembrana plasmáticaRE-fagiacontrol genéticoaplicaciones biomiméticas

Más Videos Relacionados

Drosophila Embryo Preparation and Microinjection for Live Cell Microscopy Performed using an Automated High Content Analyzer
05:52

Drosophila Embryo Preparation and Microinjection for Live Cell Microscopy Performed using an Automated High Content Analyzer

Published on: January 19, 2021

9.2K
Bottom-Up In Vitro Methods to Assay the Ultrastructural Organization, Membrane Reshaping, and Curvature Sensitivity Behavior of Septins
09:09

Bottom-Up In Vitro Methods to Assay the Ultrastructural Organization, Membrane Reshaping, and Curvature Sensitivity Behavior of Septins

Published on: August 17, 2022

2.8K

Videos de Experimentos Relacionados

Last Updated: Jan 7, 2026

Visualization of Caenorhabditis elegans Cuticular Structures Using the Lipophilic Vital Dye DiI
08:22

Visualization of Caenorhabditis elegans Cuticular Structures Using the Lipophilic Vital Dye DiI

Published on: January 30, 2012

17.7K
Drosophila Embryo Preparation and Microinjection for Live Cell Microscopy Performed using an Automated High Content Analyzer
05:52

Drosophila Embryo Preparation and Microinjection for Live Cell Microscopy Performed using an Automated High Content Analyzer

Published on: January 19, 2021

9.2K
Bottom-Up In Vitro Methods to Assay the Ultrastructural Organization, Membrane Reshaping, and Curvature Sensitivity Behavior of Septins
09:09

Bottom-Up In Vitro Methods to Assay the Ultrastructural Organization, Membrane Reshaping, and Curvature Sensitivity Behavior of Septins

Published on: August 17, 2022

2.8K

Área de la Ciencia:

  • Biología Celular; Biomimética; Ciencia de Materiales

Sus antecedentes:

  • Las cutículas de los insectos poseen estructuras a nanoescala con propiedades funcionales, que inspiran aplicaciones biomiméticas.
  • Los mecanismos celulares subyacentes al nanopatterning cuticular no se comprenden bien.
  • El gen de Drosophila gore-tex/Osiris23 (gox) se sabe que controla la formación de nanoporos en los órganos olfativos.

Objetivo del estudio:

  • Elucidar los mecanismos celulares de la formación de nanoporos en las cutículas de insectos.
  • Investigar el papel de la proteína residente del RE Gox en el nanopatterning cuticular.
  • Comprender el control genético de la fabricación de estructuras de matriz extracelular a nanoescala.

Principales métodos:

  • Imágenes de microscopía electrónica 3D de estructuras completas de pelos de insectos.
  • Análisis de la interacción entre el retículo endoplasmático (RE) y el tráfico de la membrana plasmática.
  • Investigación del papel de la RE-fagia y sus reguladores (Gox, Ref(2)P, Dinamina).

Principales resultados:

  • La formación de nanoporos implica una novedosa interacción bidireccional entre el RE y la membrana plasmática.
  • La proteína residente del RE Gox estimula la RE-fagia a través de Ref(2)P e inicia la endocitosis.
  • La dinamina media la endocitosis y mantiene la RE-fagia, contribuyendo al nanopatterning.

Conclusiones:

  • La RE-fagia se reutiliza para la remodelación de la membrana plasmática y la fabricación de estructuras a nanoescala.
  • Este estudio revela un nuevo mecanismo para el nanopatterning de la cutícula de insectos.
  • Los hallazgos proporcionan información sobre el control genético de estructuras biomiméticas a nanoescala.