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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
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Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
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Updated: Jan 7, 2026

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Actualizaciones sobre Injertos y Sustitutos Óseos

Edgard Eduard Engel1, Nelson Fabrício Gava1, Mariana Avelino Dos Santos1

  • 1Departamento de Ortopedia e Traumatologia, Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil.

Revista brasileira de ortopedia
|January 1, 2026
PubMed
Resumen

Los injertos autólogos son el estándar pero tienen limitaciones. Los nuevos sustitutos óseos sintéticos ofrecen una promesa para la reparación de defectos óseos, aunque todavía necesitan igualar la efectividad del autoinjerto para una oseointegración óptima.

Palabras clave:
cementos óseosregeneración ósearemodelación óseasustitutos óseos

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